pentobarbital will lower the extent or impact of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Look at an increase in cannabidiol dosage (determined by clinical reaction and tolerability) when coadministered with a robust CYP3A4 inducer.
buprenorphine transdermal and pentobarbital both equally maximize sedation. Steer clear of or Use Alternate Drug. Restrict use to people for whom different cure options are inadequate
pentobarbital will lower the extent or effect of nateglinide by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.
pentobarbital will lessen the extent or influence of conivaptan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will reduce the extent or influence of phenytoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor.
pentobarbital will lower the level or influence of tacrolimus by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Contraindicated (1)pentobarbital will lower the level or result of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or impact of bosentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Mysterious.
pentobarbital will lower the extent or effect of guanfacine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Strong or average CYP3A4 inducers check here drastically minimize guanfacine plasma concentrations and elimination half-existence.
pentobarbital will lower the level or impact of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. The efficacy of hormonal contraceptives might be lowered.
pentobarbital will minimize the level or influence of theophylline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will reduce the level or outcome of pantoprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.
pentobarbital will lower the extent or influence of atorvastatin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will reduce the level or outcome of trazodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.